The MDR-TB epidemic—a status report

RESIST-TB authored (C. R. Horsburgh, Jr, C. D. Mitnick, C. Lange) editorial in the International Journal of Tuberculosis and Lung Disease February edition:


Despite its recognition over 28 years ago, the magnitude of the impact of drug resistance of M. tuberculosis on TB control has long been under-appreciated. We now realize that MDR strains of M. tuberculosis are spreading by primary transmission and not merely developing through therapeutic misadventure, that cure rates are abysmal,4,5andthat the level of resistance to drugs in addition to INH and RMP is often astonishingly high.

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