REPORTS AND PUBLICATIONS
Progress in the Fight Against DR-TB (2024)
For World TB Day 2024, we report recent DR-TB achievements and challenges.
Our Annual Report details the progress that each working group made in 2023, as well as sets goals for 2024.
Domínguez, J., Boeree, M. J., Cambau, E., Chesov, D., Conradie, F., Cox, V., Dheda, K., Dudnyk, A., Farhat, M. R., Gagneux, S., Grobusch, M. P., Gröschel, M. I., Guglielmetti, L., Kontsevaya, I., Lange, B., van Leth, F., Lienhardt, C., Mandalakas, A. M., Maurer, F. P., Merker, M., … TBnet and RESIST-TB networks
Progress in the Fight Against DR-TB (2023)
For World TB Day 2023, we report the achievements and challenges in DR-TB across the past couple of years.
Global availability of susceptibility testing for second-line anti-tuberculosis agents (2022)
A. Lazarchik, A. U. Nyaruhirira, C-Y. Chiang, F. Wares, C. R. Horsburgh, Jr.
Our Annual Report details the progress that each working group made in 2022, as well as sets goals for 2023.
Our Annual Report details the progress that each working group made in 2021, as well as sets goals for 2022.
Our Annual Report details the progress that each working group made in 2020, as well as sets goals for 2021.
Progress in the roll-out of multidrug-resistant tuberculosis (MDR-TB) treatments (May 2020)
M. Heng, S. Allmendinger, C-Y. Chiang, A. Trébucq, C. R. Horsburgh
Our Annual Report details the progress that each working group made in 2019, as well as sets goals for 2020.
Progress in global rollout of new multidrug-resistant tuberculosis treatments (September 2019)
K. Held, S. McAnaw, C-Y. Chiang, A. Trebucq, C. R. Horsburgh, Jr.
K. Mezwa, S. McAnaw, C-Y. Chiang, A. Trébucq, C. R. Horsburgh
A State of the Art Article Krakauer, E. L.; Dheda, K.; Kalsdorf, B.; Kuksa, L.; Nadkarni, A.; Nhung, N. V.; Selwyn, P.; Shin, S.; Skrahina, A.; Jaramillo, E.
A State of the Art Article, E. A. Talbot, M. Pai
Management of patients with multidrug-resistant tuberculosis (June 2019)
A State of the Art Article, C. Lange, R. E. Aarnoutse, J. W. C. Alffenaar, G. Bothamley, F. Brinkmann, J. Costa, D. Chesov, R. van Crevel, M. Dedicoat, J. Dominguez, R. Duarte, H. P. Grobbel, G. Gunther, L. Guglielmetti, J. Heyckendorf, A. W. Kay, O. Kirakosyan, O. Kirk, R. A. Koczulla, G. G. Kudriashov, L. Kuksa, F. van Leth, C. Magis-Escurra, A. M. Mandalakas, B. Molina-Moya, C. A. Peloquin, M. Reimann, R. Rumetshofer, H. S. Schaaf, T. Sch ¨on, S. Tiberi, J. Valda, P. K. Yablonskii, K. Dheda
Series editors: Horsburgh, C. R; Lange, C.; Mitnick, C
Health care gaps in the global burden of drug-resistant tuberculosis (February 2019)
A State of the Art Article, Cox V.; Cox, H.; Pai, M.; Stillo, J.; Citro, B.; Brigden, G.
The MDR-TB epidemic—a status report (February 2019)
Horsburgh C. R.; Mitnick, C. D.; Lange, C.
What will it take to eliminate drug-resistant tuberculosis? (May 2019)
A State of the Art Article, Kendall E. A.; Sahu, S.; Pai, M.; Fox, G. J.; Varaine, F.; Cox, H.; Cegielski, J. P.; Mabote, L.; Vassall, A.; Dowdy, D. W.
State of the Art Article, Nathavitharana R. R.; Lederer, P.; Tierney, D. B.; Nardell, E.
Our Annual Report details the progress that each working group made in 2018, as well as sets goals for 2019.
Results of The Union DR-TB Working Group Surveys, 2017 and 2018
Horsburgh C.R., Chiang C-Y, Trébucq A, Mezwa K, Held K
Has compassionate use ever sunk a drug? (February 2018)
Mcanaw S, Muller A, Mitnick C, Horsburgh C.R.
Hoddinott G, Staples S, Brown R, Simwinga M, Mubekapi-Musadaidzwa C, Hesseling AC, Hendricks G, De Koker P, McKenna L
Seddon JA, Weld ED, Schaaf HS, Garcia-Prats AJ, Kim S, Hesseling AC
Statistical considerations for pediatric multidrug-resistant tuberculosis efficacy trials (May 2018)
Kim S, Seddon JA, Garcia-Prats AJ, Montepiedra G
Garcia-Prats AJ, Svensson EM, Weld ED, Schaaf HS, Hesseling AC
Preclinical tools for the evaluation of tuberculosis treatment regimens for children (May 2018)
Tucker EW, Dooley KE
The burden of multidrug-resistant tuberculosis in children (May 2018)
Jenkins HE, Yuen CM
MDR-TB in children: back to the basics (May 2018)
Horsburgh C.R, Gupta A
Our Annual Report details the progress that each working group made in 2017, as well as sets goals for 2018.
Mezwa K, McAnaw S, Chiang C-Y, Trébucq A, Horsburgh C.R
RESIST-TB Site Development Report and Site Development Tool (2017)
The Site Development Report outlines efforts to expand the number of possible MDR-TB clinical trial sites in areas with access to patients and interest in becoming trial sites. RESIST-TB developed a Site Development Tool to determine whether those sites either had adequate capacity or needed site development activity.
Our Annual Report details the progress that each working group made in 2016, as well as sets goals for 2017.
Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda (May 2016)
There are numerous challenges in delivering appropriate treatment for multidrug-resistant tuberculosis (MDR-TB) and the evidence base to guide those practices remains limited. This piece presents the third updated Research Agenda for the programmatic management of drug-resistant TB (PMDT), assembled through a literature review and survey.
Global MDR-TB Clinical Trials Landscape Meeting Supplement
(2016) Based on the results of the first global MDR-TB Clinical Trials Landscape meeting held in 2014, this supplement includes a collection of manuscripts that address key topics including both methodological issues and agent-specific reports. These articles provide an in-depth discussion of the rationale behind current MDR-TB clinical trials as well as important insights to drive future research.
Monitoring Compassionate Use of New Drugs for Tuberculosis
With support from the Firland Foundation, RESIST-TB investigated mechanisms for accessing drugs prior to regulatory approval and surveyed key providers and advocates on their experience attempting to gain access to new TB drugs through compassionate use or similar pre-approval mechanisms. The findings from this project are detailed in this report, “Monitoring Compassionate Use of New Drugs for Tuberculosis.
Presents a core set of efficacy and safety definitions as well as other important considerations in DR-TB clinical trials work.
Proposes that reports of molecular DST results should include information on specific mutations that affect resistance to chose an appropriate treatment regimen.
Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda (May 2016)
Identifies priorities for coordinated research in PMDT that could fill longstanding gaps barring expanded treatment access, including: shorter treatment regimens, knowledge of disease burden without representative data, and treatment for latent TB infection in household contacts of known DR-TB patients.